Yes, you can use any Casper mattress on an adjustable bed frame. Whether you choose a memory foam mattress like The Casper or a hybrid mattress like the Original Hybrid or Wave Hybrid Snow, just make sure the mattress size matches the size of your base (e.g. a king size mattress with a king size adjustable bed). We recommend the Casper Lifestyle Adjustable Base Lift, Pro, or Max.
Learn more about which mattress is right for adjustable base.